Gardasil Drug Interactions

Gardasil drug interactions with other medications, such as anticoagulants or immunosuppressants, can potentially cause bleeding under the skin or cause the Gardasil to not work as well as it should. It is not known whether Gardasil will interact with most other vaccines. Therefore, talk to your healthcare provider about whether the benefits of taking Gardasil outweigh the risks.

 

An Overview of Gardasil Drug Interactions

Gardasil® (Quadrivalent Human Papillomavirus [Types 6, 11, 16, and 18] Recombinant Vaccine) can potentially interact with many drugs. Some of the drugs that may lead to Gardasil interactions include:
 
  • Anticoagulants, including:
o Dalteparin (Fragmin®)
o Enoxaparin (Lovenox®)
o Heparin
o Warfarin (Coumadin®, Jantoven®)
  • Immunosuppressants, such as:
o Certain monoclonal antibodies, including:
o Corticosteroids, such as:
      • Betamethasone (Celestone®)
      • Corticotropin
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)
o Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
o Lenalidomide (Revlimid®)
o Methotrexate (Rheumatrex®)
o Mycophenolate (CellCept®)
o Nelarabine (Arranon®)
o Sirolimus (Rapamune®)
o Tacrolimus (Prograf®)
o Thalidomide (Thalomid®)
o Trimetrexate (NeuTrexin®)
  • Other vaccines.
     
(Gardasil Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;